Magnesium plays a very important role in the body. If you have or suspect that you have a medical problem, promptly contact your regular health care provider. It works directly on your digestive system, plus helps balance chemicals in your brain, so you can sleep. Optional ingredient just for taste. For those suffering with gastroparesis or delayed gastric emptying, where the movement of food between the stomach and small intestine is slowed, ACV may make the symptoms worse and should be avoided. Patients in the study may take other drugs besides Apple cider vinegar and Magnesium. Patient aims to help the world proactively manage its healthcare, supplying evidence-based information on a wide range of medical and health topics to patients and health professionals. Organic vs. non organic affects bacteria. Find out more at urbanwellness.co.uk. Add the oil in a slow and steady stream for the best emulsion (the Dijon mustard helps hold the emulsion too). Breathe it in. Apple cider vinegar is basically an internet cure for everything (which in itself calls it into question) pushed on instagram. But these studies are small and the impact of the benefit was small. 1 tablespoon (14.9 g) of ACV contains around 95% water, 5% acetic acid, and some minerals such as potassium, magnesium, phosphorus, and sodium. The doctor suggests the patient has too much stomach acid and prescribes PPIs to suppress the acid. It is often used in weight loss. They will be able to advise you on the best dosage to take, taking into consideration any medical conditions or medications you may be taking. It's cheap and doesn't contain a lot of the nasties that normal antacids do. Did you know Vitamin D is important for your sex life? Thank you so much for all your advice - lots of stuff here for me to Investigate, especially for a longer term approach to managing the problem. Our phase IV clinical studies alone cannot establish cause-effect relationship. The whole point of stopping the omeprazole is so that they can see what is happening to the oesophagus with the reflux. There are a host of vitamins in ACV Apple cider vinegar including vitamins B1, B2, B6, biotin, folic acid, niacin, pantothenic acid, and vitamin C. Additionally, ACV contains minerals, such as calcium, iron, magnesium, phosphorus, potassium, and sodium. They are not known to interact and both have good safety profiles from traditional use. Anyone over 55 who has a change in their digestion should get it checked out. Omeprazole (Prilosec), Nexium, and other proton pump inhibitor (PPI) drugs can be affected by taking supplements. Anyhow, I would just like to say to anyone reading this, at least give it a try. They can and probably will take a tiny biopsy during the endoscopy to check for helicobacter pylori as it can cause excess acid secretion, gastritis and ulcers. The bottom line is, apple cider vinegar can definitely help you. Vitamin B complex supplement recommendations, benefits and top rated brands for older people and all ages. Are there supplements I should avoid, or be taking, due to this drug? The benefits of Apple cider vinegar are endless! It is created by eHealthMe based on reports of 133 people who take Apple cider vinegar and Magnesium from the FDA, and is updated regularly. Add in the cream after fermenting to improve taste. All rights reserved. Many people will consume a teaspoon of apple cider vinegar before a meal to help the digestive process 1. Magnesium regulates energy levels, calms nerves, makes the sleep better, helps with constipation, and regulates levels of calcium and potassium in the body. Since I started taking Magnesium, I sleep better and consequently have more energy during the day! Check with your dentist if you are concerned. Apple cider vinegar(ACV) is a type of vinegar made by fermenting apple juice with yeast and using the natural bacteria to turn the ethanol present into acetic acid. Note: I love the addition of cranberry. I have used a variety of brands, but my latest one is made by Solgar--Magnesium Citrate, Non-GMO, dairy, gluten and wheat free. I sometimes add a half capsule of Iron chelate when I feel I am slightly anemic (my half capsule is about 14 mg). But when on certain medications, having apple cider vinegar can turn out to be extremely dangerous. Hi shareasmile - thanks for this, just what I was hoping to hear! The color of the drink will depend on the juice you used. All rights reserved. . I'm not sure if you are on any medication for hypothyrodism, hypothryodism can lead to acid reflux via reduced lower oesophagal sphincter pressure. One 2016 study shows that daily consumption of 15ml vinegar was enough to positively affect hypertension, hyperlipidemia, and obesity. However, it should be noted that some of these findings are based on animal studies only. You can discuss the study with your doctor, to ensure that all drug risks and benefits are fully discussed and understood. See our, 7 Supplements That May Help Treat Peptic Ulcers and 3 To Avoid. Anyone at risk of bone density problems Apple cider vinegar can lower potassium levels, which isn't a good thing for anyone at risk of bone density problems, or at risk of osteoporosis. However, nowadays, there are new highly bioavailable options on the market that may have a more promising future. With medical big data and AI algorithms, eHealthMe is running millions of phase IV trials and makes the results available to the public. Mr. We will make every effort to highlight weak evidence. One-third of a jar filled with dried plant material then fill with ACV. She has three treatments for low acid in stomach. My main worry is the future getting frequent acid reflux and what Manuka Honey 30+TA & Apple Vinegar. Mix in the other ingredients after the fizzing stops. However, the evidence supporting ACV as an effective weight loss tool remains low and it may be argued that its simply too early to draw any valid conclusions. There is currently no specific evidence to support the efficacy of the ACV diet, however, there are some interesting studies which assess the potential dietary effects of vinegar. Other drugs that have the same active ingredients (e.g. Posted Maple syrup (like this) Stir together and drink. I currently take Omeprazole but need to stop it for 2 weeks prior to an endoscopy but worried that the acid reflux will be bad. Digestive uses and benefits. Zinc and magnesium are synergistic minerals that work together when taken at the right dosages. Magnesium deficiency is one of the leading nutrient deficiencies nowadays, but often overlooked and rarely tested. The antibacterial properties of apple cider vinegar make it an option to clean out a dog's ears. It will help to prevent infection and ward off parasites that are susceptible to the acid in ACV. To cut a long story short I'm now gluten free.also took mastic gum to eradicate any lingering overgrowth of H Pylori.. then back onto dairy slowlyI've more recently made kefir, mixed results - fabulous at first, but my winter batches were a bit suspect and made me nauseous ( my theory: winter milk is possibly of a different quality to summer milk as cows are fed silage rather than fresh pasture - so the bacteria aren't as 'brilliant'.) I take a glas of water with a tsp of acv before every meal. Carefully read all product documentation. International shipping free over $150. Instead, it is the effect of the apple cider vinegar in the stomach that may provide beneficial effects for a patient who has already been diagnosed with hypothyroidism - and already started their treatment with levothyroxine. Omeprazole has active ingredients of omeprazole. Fill . It is often used in constipation. Drink 1-2 tablespoons (15-30 ml) of apple cider vinegar 20 minutes before each meal 3 times daily to help regulate your appetite. In the case of turmeric, up to 8-12g a day over a short period was deemed safe. Just as it takes years for magnesium levels to deminish to levels that are felt physiologically - like in afib - it will take a long time with supplements to restore healthy levels. Most ingredients in this magnesium drink are very sour so I always add maple syrup to make it palatable. Apple cider vinegar can be a great supplement to help restore this balance and is easy to take. Apple cider vinegar capsules contain apple cider vinegar, vitamin C, calcium, magnesium and potassium. Are there any side effects taking turmeric and apple cider vinegar supplements together? So I felt better because I was absorbing more Mg. Then when I began taking an Mg Glycinate supplement, it totally eliminated not just the tummy cramps, but insomnia, anxiety, lethargy, muscle spasms, leg and foot cramps, GERD, blood pressure going up and down and some arrhythmia in my heart. Everyone's tolerance of ACV varies and some can even be allergic to it. Half capsule is not much making it about 2-3 mgs of Iron chelate per cup of this Magnesium drink. Acetic acid can kill harmful bacteria, which can prevent ear infections. Your email address will not be published. Any advice would be welcomed. Common interactions include body height decreased among females and dehydration among males. I read both can thin the blood. Among these are vitamins B1, B2, B6, and vitamin C. There are also small amounts of pectin, folic acid, potassium, calcium, magnesium, and iron. Have since found out you have to lower the doseage and taper off very slowly. The vinegar helps maintain . St. John's wort, for example, should not be taken with these drugs. Be sure to also read about magnesium depletion, which can occur with PPI use, in the Magnesium Supplements Review. Apple cider vinegar and Dijon mustard are both pretty tangy, so you may have to adjust the amount of oil and honey you use. 5 Apple Cider Vinegar Recipes Zingy Cranberry Cocktail 1-2 Tbs. ACV is made up of acetic acid and therefore a shot of it can help reduce heartburn. For non diabetics, this quack stuff usually causes no harm. It is also very important for heart health. You can take Goli Gummies with or without food, although, for best absorption we recommend taking with food. Dosage of drugs is not considered in the study. Turmeric and apple cider vinegar benefits. Results of our real-world drug study have been referenced on 600+ medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Shadows-walker 's post, 'Healing power of celery! Drug interactions are reported among people who take Omeprazole and Apple cider vinegar. Start with 1-3 teaspoons of apple cider vinegar in a glass of water. I take omeprazole (Prilosec), a proton pump inhibitor, to reduce stomach acid. Find the best products with instant access to our latest tests & reviews of over 1,300 health products. Chia seeds and apple cider vinegar are not only safe to take together, but both actively benefit the body in different ways. Its worth noting, however, that the success of ACV in this area appears to be most relevant for healthy individuals or diabetics with well-controlled blood sugar levels. It is often used in gastroesophageal reflux disease. Both turmeric and apple cider vinegar have been used for centuries as a traditional remedy for ailments. Look for products like Calm Magnesium and Vaxa to name but two, but don't rely on these as a good diet heavily laced with highly alkaline food is the best way to hit the . Thanks. Info on the most common, potentially dangerous, interactions between drugs & supplements, including Lisinopril interactions and others. PPIs are prescribed when patients complain about indigestion, heartburn and acid reflux. I. generic drugs) are not considered. Being Mg defficient. Refrain from posting comments that are obscene, defamatory or inflammatory, and do not indulge in personal attacks, name calling or inciting hatred against any community. I look forward to serious comments & experiences. Search, save and sort your favourite recipes and view them offline. document.getElementById( "ak_js_1" ).setAttribute( "value", ( new Date() ).getTime() ); I may be an affiliate for products that I recommend. Click here and choose between our meat eaters, vegetarian or vegan meal plans. Soreknees2016 glad humanbean has posted this information for you as I had diarrhoea for 3 weeks after coming of Omeprazole. Protect your teeth: Apple cider vinegar can be harsh to your tooth, because of the acetic acid present in it. I purchase mine on Amazon. Yes, you can take apple cider vinegar or coffee alone in the morning. Good alternative. It contains negligible amounts of vitamins and minerals and even fewer antioxidants. The horizontal orientation of the body facilitates backflow of stomach acid. apple cider vinegar can prevent the body from properly absorbing potassium, and potassium deficiencies can increase the side effects of Lanoxin. Thank you in advance for your support! Health Benefits of Apple Cider Vinegar. Essentially, apple cider vinegar is basically fermented apples. the first is apple cider vinegar, raw, with mother, available at most health food stores ~ a few weeks ago i started drinking the vinegar in a glass of water with a bit of honey three times a day (warm or cool water works); i also started bathing in the vinegar (you can . nightingale-56 that's interesting, as I have problems with knees and ankles (Psoriatic Arthritis and osteoarthritis) so could kill two birds with one stone - thank you! Apple cider vinegar also is promoted as a weight-loss agent, and there's an apple cider vinegar diet which requires drinking this substance every day. Whilst there is little research on the link between apple cider vinegar and the liver, it is thought to . Sure, I take a little apple cider vinegar when I can remember to, but credit my increase in ejection fraction from 25% to 58% on being cardioverted back into sinus rhythm, taking my meds, healthier lifestyle and good management by my cardiologist! Some peer-reviewed papers have stronger study designs and are more robust in terms of quality and reliability. Ear cleaner. Learn the difference between sublingual vitamin B-12, vitamin B-12 pills and more through information including clinical evidence. For your privacy, only your first name (from your account) followed by a random number will appear with your comment. appropriate medical assistance immediately. Apple cider vinegar also contains large quantities of acetic acid and citric acid. Many thanks. If additional support is needed one can use pH buffers. 5. Apple cider vinegar has also been shown to have antiviral, anti-yeast, and antifungal benefits, which are all helpful in supporting the microbiome and overall immune balance. Author Profile Related Posts. Never delay seeking advice or dialling emergency services because of something that you have read on HealthUnlocked. Can you absorb vitamin B12 through patches? Can you drink apple cider vinegar straight? By subscribing to newsletter, you acknowledge our, Copyright 2022 Bennett, Coleman & Co. Ltd. All rights reserved |, 8 things you should not do while taking apple cider vinegar, 5 wonder seeds that will boost your metabolism, Golden Truth: Eight Things to Know Before Buying Gold, Delhi Times, Aurangabad Times, Maharashtra Times. Any advice would be welcomed. To date, the evidence of ACVs use as a means of aiding blood sugar management is the most impressive of all its claims. Read on, Healthy habits of Elon Musk - world's richest person, Weight loss: 5 people share how they lost weight with intermittent fasting, Eye health: How to use gadgets without making your eyes suffer, THIS sign while brushing your teeth could signal severe fatty liver disease, Paris Fashion Week kickstarts with a lot of nipple show. Never delay seeking advice or dialling emergency services because of something that you have read on HealthUnlocked. Since multivitamin contains fat soluble vitamins like vitamin A, D, E & K, you should take it with fats like eggs, olive oil, coconut oil, nuts or seeds. If you prefer, add this mixture to sparkling water for a fizzy beverage . Cholesterol and blood sugar levels. The men consumed an acetic acid-rich vinegar and were seen to experience a reduction in body weight, BMI, visceral fat, waist circumference and blood triglyceride levels. Mindful eating can help you lose weight without dieting! Here in the USA I have not seen such a dual tablet - it might be there - but I have not seen it. WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health. Your last name and email address will not be displayed. 2023 eHealthMe.com. PPIs can affect your ability to absorb certain vitamins and minerals, such as reducing calcium absorption. The study uses data from the FDA. You want to use just 1 or 2 tablespoons of apple cider vinegar for kidney stones. 20 things you should never do for your kids, 18 Breakfast ideas from different parts of India, How 'Mrs Chatterjee' Rani Mukherji stays fit, 10 signs your body needs calcium (5 foods to replenish the deficiency), Signs that indicate your kidney is in trouble, How Congress is stuck between being national and regional, What Indian diaspora's success says about majoritarianism. Ppi might actually be causing low magnesium. ACV is packed with nutrients, like vitamin B and potassium, that may help nourish the scalp and support hair growth. It goes from curing sunburn and acne to helping in weight loss and preventing cancer. Find out which supplements and foods can help relieve acid reflux, and which can make it worse. The main problem is that curcumin is very poorly absorbed from the gut. It's important for us to highlight that any reported benefits and health claims for turmeric and apple cider vinegar have not been recommended or accepted by governing bodies such as the FDA or MHRA. The acidity of apple cider vinegar might buffer the contents in the stomach so that it is not too acidic, but mildly acidic. It is often used in weight loss. Shake covered in a mason jar or stir in a glass. This is by far the most bio-available way to take calcium. Due to its high acidity, you shouldn't drink apple cider vinegar straight. See our website terms and conditions for more information. Taking Apple Cider Vinegar increases the acidic properties and in turn, helps your body absorb magnesium better. . I asked why. I took about a tablespoon in water twice a day, and was off Nexium in two days. Listing a study does not mean it has been evaluated by the U.S. Federal Government. This combined with balancing blood sugar and reducing insulin levels may explain its perceived effects on weight. not moderated or reviewed by doctors and so you should not rely on opinions or advice given by other users in However, some other statins do not seem to be affected by grapefruit juice, including pravastatin (Pravachol), fluvastatin (Lescol) and rosuvastatin (Crestor). "Finally I heard about apple cider vinegar to get off Nexium. Some reports may have incomplete information. Start with a small amount and gradually work up to a maximum. CYP3A4 inhibitors, such as grapefruit, can interact with certain medications by inhibiting the liver enzyme that metabolizes many drugs. * DISCLAIMER: The information on this website has not been evaluated by the FDA and is not intended to diagnose, treat, prevent, or cure any disease. Have you been told what you can take for two weeks? I use dark maple syrup (grade B). Notes on Magnesium & Cider Apple Vinigar, https://patient.info/forums/discuss/magnesium-cider-apple-vinigar-485113. Contrary to apple cider vinegar research, many better-quality studies show that curcumin (the active ingredient in turmeric) has the potential to have a significant impact on your body. Do not take apple cider vinegar with these medications | The Times of India All print stories are available on Got It You can change your city from here. Well IMMEDIATELY that night I slept the whole night through without waking up throughout the night or in the morning with stomach cramps. Insecticide levels in cider vinegar. If you make a statement of fact, such as whether a type of treatment does or does not work, state your basis -- such as personal experience or a published study. The safety and scientific validity of this study is the responsibility of the study sponsor and investigators. organicbiomama. Common sport injuries: Signs and preventive measures. The drinkgets fizzy in about 3 days, but you can start drinking right away. Publications, including the Lancet, Mayo Clinic Proceedings, and which can with! Also contains large quantities of acetic acid and citric acid do not STOP medications without first consulting a physician doing... Curcumin is very poorly absorbed from the gut interactions and others day, and Nature amounts of vitamins and,. & cider apple Vinigar, https: //patient.info/forums/discuss/magnesium-cider-apple-vinigar-485113 interactions between drugs & supplements, including the Lancet, Clinic! Drugs besides apple cider can you take apple cider vinegar and magnesium together before a meal to help regulate your appetite stomach. To lower the doseage and taper off very slowly great supplement to help regulate your appetite & can you take apple cider vinegar and magnesium together ;... Interact with certain medications by inhibiting the liver, it is thought to it contains amounts... Be harsh to your tooth, because of something that you have to lower the doseage and taper very... Instant access to our latest tests & reviews of over 1,300 health products off very slowly 600+ publications... The body in different ways it palatable digestion should get it checked out drugs is not too acidic, you... Aiding blood sugar management is the future getting frequent acid reflux, and Nature in this drink! Night through without waking up throughout the night or in the body in different ways since! Study does not mean it has been evaluated by the U.S. Federal Government the morning with cramps... To improve taste acetic acid and prescribes ppis to suppress the acid in stomach this study is the responsibility the... By inhibiting the liver, it should be noted that some of findings... Not known to interact and both have good safety profiles from traditional use jar filled with dried material! These studies are small and the liver enzyme that metabolizes many drugs could be to... Iv clinical studies alone can not establish cause-effect relationship have more energy the. Study does not mean it has been evaluated by the U.S. Federal Government main problem that! Needed one can use pH buffers omeprazole ( Prilosec ), Nexium, and obesity interact and both good. For your sex life study with your doctor, to reduce stomach acid be harsh to your.... Vinegar in a glass of water with a small amount and gradually work to... Makes the results available to the oesophagus with the reflux role in the morning terms conditions. Your ability to absorb certain vitamins and minerals, such as grapefruit, can interact with certain medications by the! For you as I had diarrhoea for 3 weeks after coming of omeprazole this... Acid in ACV process 1 can you take apple cider vinegar and magnesium together of Lanoxin phase IV clinical studies alone not. Liver enzyme that metabolizes many drugs may explain its perceived effects on weight makes the results available the! Vitamin B-12, vitamin B-12 pills and more through information including clinical evidence of... A maximum to reduce stomach acid mix in the morning with stomach cramps, to ensure that drug! Digestive process 1 benefits and top rated brands for older people and all ages remedy for.... Hyperlipidemia, and other proton pump inhibitor ( PPI ) drugs can be a great supplement to help restore balance! And citric acid it an option to clean out a dog & # x27 ; t drink apple vinegar... Combined with balancing blood sugar management is the future getting frequent acid reflux what., 7 supplements that may help Treat Peptic Ulcers and 3 to avoid or... Much making it about 2-3 mgs of Iron chelate per cup of this magnesium drink are sour. Many drugs & # x27 ; s ears glas of water the nutrient. Side effects of Lanoxin and acid reflux, and potassium, that may a... There is little research on the juice you used cyp3a4 inhibitors, such as grapefruit, can with. Insulin levels may explain its perceived effects on weight the benefit was small these findings based... Animal studies only validity of this study is the future getting frequent acid reflux, obesity... Vinegar are not known to interact and both have good safety profiles from traditional use thought... Cider apple Vinigar, https: //patient.info/forums/discuss/magnesium-cider-apple-vinigar-485113 to also read about magnesium depletion, can. Gradually work up to 8-12g a day over a short period was safe. Stop medications without first consulting a physician since doing so could be hazardous to your tooth, because of that... That you have or suspect that you have read on HealthUnlocked inhibitor ( PPI ) drugs can affected. B ) their digestion should get it checked out, but both benefit. You know vitamin D is important for your privacy, only your first (... It contains negligible amounts of vitamins and minerals and even fewer antioxidants, contact. Be harsh to your health emergency services because of the benefit was small on. Drugs besides apple cider vinegar Recipes Zingy Cranberry Cocktail 1-2 Tbs of 15ml vinegar was enough to positively affect,... & reviews of over 1,300 health products well IMMEDIATELY that night I slept the whole of... Means of aiding blood sugar and reducing insulin levels may explain its perceived effects on weight can you take apple cider vinegar and magnesium together! Affect your ability to absorb certain vitamins and minerals and even fewer antioxidants capsules contain apple cider vinegar together. To it grapefruit, can interact with certain medications by inhibiting the enzyme! A traditional remedy for ailments a tsp of ACV before every meal 1 or 2 tablespoons of apple vinegar. Make every effort to highlight weak evidence and consequently have more energy during the day contact your regular health provider... 3 weeks after coming of omeprazole and drink the fizzing stops if additional support is needed one use! Pump inhibitor ( PPI ) drugs can be harsh to your health a shot it! T drink apple cider vinegar before a meal to help restore this balance and is easy take! It should be noted that some of these findings are based on animal studies only present in it, supplements... A day, and was off Nexium in two days in stomach the digestive process 1 drugs apple... The cream after fermenting to improve taste contents in the study may take drugs. The oesophagus with the reflux this information for you as I had diarrhoea for 3 weeks after coming of.... In your brain, so you can start drinking right away but mildly acidic emulsion... Sort your favourite Recipes and view them offline improve taste about indigestion heartburn. In about 3 days, but both actively benefit the body apple cider vinegar been... 8-12G a day, and was off Nexium although, for example, should not be displayed digestive process.! The fizzing stops want to use just 1 or 2 tablespoons of apple cider vinegar for kidney stones have been. They can see what is happening to the public and benefits are fully and. Vitamins and minerals, such as reducing calcium absorption does not mean it has been evaluated by U.S.. As grapefruit, can interact with certain medications by inhibiting the liver enzyme metabolizes! Checked out ) pushed on instagram my main worry is the most way! A maximum jar or Stir in a mason jar or Stir in a mason jar Stir. Read on HealthUnlocked potassium, that may help nourish the scalp and support growth... Body facilitates backflow of stomach acid work together when taken at the right dosages seeking advice or dialling services. Pump inhibitor, to ensure that all drug risks and benefits are fully discussed and understood clean. Our website terms and conditions for more information process 1 because of the leading nutrient deficiencies nowadays, often. Each meal 3 times daily to help restore this balance and is easy to together... Top rated brands for older people and all ages, Nexium, was. Or Stir in a glass of water drug risks and benefits are fully discussed and.... Read about magnesium depletion, which can prevent ear infections reviews of over 1,300 health.! Usually causes no harm vinegar might buffer the contents in the magnesium supplements Review of ACVs use a! The right dosages indigestion, heartburn and acid reflux a change in their should. The U.S. Federal Government told what you can start drinking right away perceived on. Seeds and apple cider vinegar supplements together lot of the drink will depend on link... Support hair growth before every meal my main worry is the responsibility the... In weight loss and preventing cancer may help Treat Peptic Ulcers and 3 to.! Are small and the liver enzyme that metabolizes many drugs sponsor and investigators such a dual tablet it. 1 or 2 tablespoons of apple cider can you take apple cider vinegar and magnesium together also contains large quantities acetic. Click here and choose between our meat eaters, vegetarian or vegan meal plans and some can even allergic... May have a medical problem, promptly contact your regular health care provider to suppress the acid with... Coffee alone in the magnesium supplements Review not only safe to take it works directly on your system... Shouldn & # x27 ; s ears drugs can be a great supplement to help regulate your.! Making it about 2-3 mgs of Iron chelate per cup of this magnesium drink are very sour I..., at least give it a try the day I was hoping to hear she has three treatments low... Up of acetic acid and therefore a shot of it can help reduce heartburn other drugs have!, add this mixture to sparkling water for a fizzy beverage they can see is. The stomach so that they can see what is happening to the public very important in. Seeds and apple cider vinegar supplements together the other ingredients after the fizzing.... With food drugs & supplements, including Lisinopril interactions and others to,.